Many drug information services struggle to generate demand. Less established drug information services create challenges in training students with drug information abilities. As queries decrease, resources become underutilized. With shortened resources, the service needs to improve to meet demand when it arises. The drug information services and training are to be developed in a more feasible approach. The study used an interview-based effectiveness evaluation method. Drug information provided by pharmacy students to physicians at a United Arab Emirates teaching hospital was assessed for quality. As part of clinical pharmacy training, proactive drug information service was provided and assessed for its effectiveness regarding physician satisfaction. In a decentralized, proactive approach, instead of waiting for a physician query, pharmacy students with their preceptor identified drug information needs in inpatients, prepared answers, and interviewed physicians for feedback. This was an exploratory qualitative interview-based study. Fifteen responses of physicians from internal medicine, pediatrics, gynecology, and obstetrics were received in a month. Students' performances were accepted by physicians for 13 cases out of 15. Students demonstrated abilities to practice drug information service under the supervision of a pharmacy preceptor. Physician feedback, preceptor evaluation, and student self-reflection in triangulation demonstrated the effectiveness of the rotation. The drug information service was accepted by physicians expressing their positive written feedback. Proactive drug information service in training pharmacy students at the study site was found to be effective. More research is required to establish more proactive drug information services in hospitals.
...Read More >>Rotaviruses are the most common cause of diarrheal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. The most common symptoms of rotavirus infection are severe watery diarrhea, vomiting, fever, and/or abdominal pain. Symptoms usually start about two days after exposure to rotavirus. Vomiting and watery diarrhea can last for three to eight days. There is no specific medicine to treat rotavirus infection. Since rotavirus disease can cause severe vomiting and diarrhea, it can lead to dehydration.
...Read More >>Tuberculosis (TB), which has afflicted humanity for thousands of years, is a worldwide pandemic disease caused mainly by Mycobacterium tuberculosis. The first-line treatment for an active TB infection is the antibiotic isoniazid (INH). Different derivatives of isoniazid are prepared by changing the chemical structure and introducing different moieties. In this review, the aim is to encapsulate different methods for the synthesis of isoniazid derivatives and their pharmacological activities. Through this exploration, insights into the potential avenues for the development of more effective treatments against TB are offered.
...Read More >>Peutz-Jeghers Syndrome (PJS) is a rare genetic disorder characterized by distinctive mucocutaneous pigmentation and gastrointestinal polyps. It is inherited in an autosomal dominant manner, with mutations in the serine/threonine kinase 11 (STK11) gene identified as the primary causative factor. PJS poses a complex challenge due to its varied clinical manifestations and increased cancer predisposition. Early diagnosis and appropriate management are crucial for improving outcomes for affected individuals. Management aims to address symptoms, prevent complications, and reduce the risk of cancer through vigilant surveillance and appropriate interventions. Proper nutrition, regular physical activity, and routine medical check-ups are crucial for managing PJS. Pharmacological and non-pharmacological interventions, as well as surgical intervention, may be necessary depending on the specific complications. This document explores the role of pharmacists in understanding, treating, and supporting individuals with PJS. Pharmacists play a crucial role in providing clear medication instructions, lifestyle recommendations, and educational materials to optimize health outcomes. They offer guidance on sleep hygiene, health promotion, disease prevention, psychosocial support, over-the-counter medication usage, iron supplementation, and drug-interaction checks. By empowering patients to take an active role in their health and facilitating support networks, pharmacists contribute significantly to the holistic management of Peutz-Jeghers Syndrome.
...Read More >>The recent advancements in the field of nanotechnology have aided in the development of targeted novel drug delivery systems. The introduction of nanosponges, a nanotechnology product, has helped overcome various conventional problems such as drug toxicity, poor bioavailability, and the release of drugs to targeted sites. Nanosponges can be loaded with various types of drugs, both hydrophilic and lipophilic, which also helps increase the bioavailability of poorly soluble drugs and molecules. They have the ability to bind to specific targeted sites and prolong drug release through controlled release from the formulation. Nanosponges are prepared by various methods, including the solvent method, quasi-emulsion diffusion method, emulsion solvent diffusion method, and ultrasound-assisted synthesis. They can be used widely for the delivery of drugs via oral, topical, and parenteral administration. Additionally, they serve as effective carriers for enzymes, vaccines, proteins, and antibodies. This article reviews the basics, preparation, application, and advancements of nanosponges.
...Read More >>Marketing and advertising are crucial in pharmaceutical manufacturing, showcasing key finishes and disseminating information about drugs, conditions, and healthcare products to professionals and consumers. However, these activities face strict regulations and ethical concerns due to their significant impact on public health and safety. This paper examines the complex landscape of broadcasting and advertising in the pharmaceutical industry, focusing on the ethical and regulatory challenges faced by industry stakeholders. It begins with an overview of the fundamental laws governing drug billing and advertising, emphasizing the importance of honesty, transparency, and integrity in all marketing efforts. The paper then explores the regulatory framework overseeing drug promotion and sales, highlighting key guidelines set by bodies such as the FDA in the U.S. and the EMA in Europe. These regulations cover various aspects of drug marketing, including content requirements, risk and side effect disclosures, and interactions with healthcare professionals (Bailey, 2001). The paper discusses the impact of mathematical and public television rules, direct-toconsumer advertising, and personalized shopping trends. It argues that ethical issues shape drug marketing strategies, addressing overpromotion, misleading claims, and potential conflicts of interest. By examining the ethical and regulatory landscape, the paper provides insights into best practices for drug advertising, emphasizing compliance with regulations, adherence to ethical standards, and the commitment to providing balanced and accurate information to ensure the safe and effective use of pharmaceuticals.
...Read More >>Complementary and Alternative Medicine, known as CAM, refers to a wide range of healing and healthcare practices that are not considered conventional treatments. These practices are often used alongside or as an alternative to traditional healing methods. CAM approaches emphasize a holistic approach to health, considering the mind, body, and spirit. They encompass a variety of remedies, including acupuncture, herbal medicine, chiropractic care, naturopathy, yoga, meditation, and more. These treatments often prioritize prevention, self-care, and natural healing processes. CAM practitioners aim to address the root causes of illness and promote overall well-being. One of the key principles of CAM is personalized care. Practitioners take into account each patient's unique needs and preferences, adapting treatments accordingly. This comprehensive approach considers the patient's physical, emotional, and spiritual health. While CAM practices have been around for many years, their popularity has increased significantly in recent times. Many people are drawn to CAM because of its focus on holistic healing, non-invasive methods, and minimal side effects. CAM also encourages patients to take an active role in their health and well-being. However, it's important to note that CAM should not be seen as a replacement for conventional medical care. It is best used in conjunction with evidence-based practices to ensure comprehensive and effective treatment. Patients should discuss CAM options with their healthcare providers and make informed decisions about their healthcare choices. Complementary and alternative medicine offers a wide range of treatments and approaches that can complement traditional medical care. With its emphasis on personalized and holistic healing, CAM provides an alternative path for individuals to enhance their well-being. Nevertheless, it's crucial to approach CAM objectively, seek guidance from healthcare professionals, and make informed decisions based on individual needs.
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